Resources

The Pharmaceutical Manufacturing Plan for Africa (PMPA) envisions an Africa where there is significantly reduced reliance on pharmaceutical imports and reduced proliferation of sub-standard and falsified (SF) medical products on the continent. To contribute to the PMPA agenda, the African Medicines Regulatory Harmonization (AMRH) initiative was established through the African Union Development Agency-NEPAD (AUDA-NEPAD), in 2009 and first launched in the East African Community (EAC) in 2012.

While two malaria vaccines are now recommended by the World Health Organization for use in African children, there remains a need for next-generation vaccines that are more efficacious, durable, and cost-effective, and that require fewer doses.One promising approach is the development of multistage vaccines targeting both the pre-erythrocytic and asexual blood stages of the malaria parasite’s lifecycle. In May 2023, under the Innovations in Malaria Vaccine Development contract, the US Agency for International Development’s Malaria Vaccine Development Program and PATH convened a panel of experts in malaria, vaccine development, regulatory affairs, and the conduct of clinical trials in Africa, Europe, and the United States to consider and inform the development of a comprehensive clinical development plan for a multistage malaria vaccine.This report summarizes the discussions held during the consultation and outlines the experts' key recommendations to inform a clinical development plan.

Advocacy is a powerful tool for advancing health conversations to policy action and budget allocations. Since 2002, PATH has partnered with the Government of Uganda to implement impactful projects and programs that promote health equity. Our policy advocacy agenda in Uganda has been critical in supporting the adoption, implementation and financing of smart policies that advance the realization of universal health coverage in Uganda. In the second half of 2023, PATH’s advocacy and policy team in Uganda undertook an effort to comprehensively document its tremendous impact on policies for women and children over the past five years. Most of the policy advocacy achievements documented were a result of strong collaboration and partnerships with key decision-makers in government, including both elected and appointed leaders (political and technical), the media, the private sector, and the civil society organizations that continue to passionately advance the advocacy agenda with a strong focus on universal health coverage (UHC). The resources and videos below are the result of this process and were shared with PATH’s key stakeholders at a high-level national learning event.

PATH Kenya, through the U.S. President's Emergency Plan for AIDS Relief/U.S. Agency for International Development (USAID)-funded Nuru Ya Mtoto project, has been advancing a comprehensive suite of health, education, economic empowerment, and social services for orphans and vulnerable children (OVC) and their caretakers. The aim is to reduce vulnerability to HIV and contribute to their overall well-being.This brief provides an overview of the process USAID Nuru Ya Mtoto undertook, in collaboration with national and county government stakeholders, local implementing partners, and community health workers, to optimize and advance a whole-of-system suite of interventions to improve service coverage among OVC households and enhance household resiliency, by facilitating graduation from USAID Nuru Ya Mtoto's OVC program.

Using a human-centered design (HCD) approach, PATH partners with ministries of health to solve an important problem—how do we increase access to safe insulin administration that is essential to high–quality diabetes self–care and clinical care?