Advancing iOWH032: Novel Antisecretory Drug for the Treatment of Cholera

PATH and partners are developing iOWH032 as a complement to oral rehydration solution for diarrheal disease treatment. Acting via inhibition of the cystic fibrosis transmembrane conductance regulator chloride channel, iOWH032 is a novel, low-molecular-weight compound intended to reduce fluid and electrolyte loss in cases of cholera toxin-induced secretory diarrhea.

Publication date: August 2017

Advancing iOWH032: Novel Antisecretory Drug for the Treatment of Cholera

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