PATH, in close partnership with Vietnam's National Expanded Program on Immunization (NEPI), has worked to increase the quality, safety, and efficiency of immunization services through the Iris Project. This fact sheet describes the project's process of testing province-wide systems improvements, identifying best practices, and encouraging other provinces to adopt the improvements. Work included updating and improving policies, training staff, and increasing community knowledge and demand for vaccination, particularly through technical updates, training of trainers, an introduction to supportive supervision, an out-of-the-cold-chain study, and an injection safety project with needle removers.