Sickle cell disease (SCD) affects 7.74 million people globally, with a rising prevalence especially in low- and middle-income countries like India, where it ranks high among tribal populations.

In Maharashtra, PATH, in collaboration with the state's public health department, is spearheading the National Sickle Cell Anemia Elimination Mission (NSCAEM). This brief outlines NSCAEM's comprehensive approach to tackling SCD, focusing on enhancing services and implementing innovative strategies in high-prevalence districts like Nandurbar and Gadchiroli.