Drawing on four decades of advocacy experience, PATH aims to play a catalytic role in advancing the practice of advocacy in health through fostering knowledge sharing, connection and collaboration among health advocates and other stakeholders. This learning brief highlights key takeaways from a virtual conversation between civil society advocates and a policymaker from Kenya, Uganda, and Burkina Faso about experiences and lessons in engaging policymakers for agenda and priority setting around PHC systems and policy implementation at national and regional levels.