Resources

Malaria progress off trackAccording to the 2025 World Malaria Report, global progress in reducing malaria deaths is falling far short. In 2024, there were 610,000 deaths—more than 3 times the global target—and an estimated 282 million cases. The report highlights intensifying risks to malaria control, including antimalarial drug resistance, parasite gene deletions that undermine diagnostic tests, insecticide resistance that reduces the effectiveness of bed nets, and the invasive mosquito Anopheles stephensi, which poses a serious challenge to urban malaria control. Extreme weather events, shifting temperatures and rainfall, and conflict and instability are also driving outbreaks and disruptions to health services. Meanwhile, global funding for malaria has plateaued at less than half the target set by the Global Technical Strategy, with recent reductions in development assistance severely impacting interventions.PATH’s commitmentPATH is dedicated to reversing stalled progress and addressing these growing threats. Our 2026-2030 strategy prioritizes strong alignment and coordination within the global malaria ecosystem. Central to this strategy are seven core pillars, recognized globally as essential to driving transmission down to zero. These pillars align with the RBM Partnership Big Push Framework, the WHO Global Technical Strategy, and the 2024 Yaoundé Declaration for a Big Push against malaria endorsed by African Ministers of Health.Through coordinated action and strategic alignment, PATH aims to maximize resources and achieve the greatest impact in the fight against malaria.

Use these slide decks to share the evidence supporting a single-dose regimen of HPV vaccine. Visit the Single-Dose HPV Vaccine Evaluation Consortium page for additional resources.

High–quality evidence assessing single–dose HPV vaccination suggests that implementing a single–dose schedule is scientifically sound, and provides the greatest public health benefit.A single–dose HPV vaccination schedule has the potential to reach more girls and avert a greater number of cervical cancer cases than reaching fewer girls with a two–dose regimen.This brief provides a list of frequently asked questions and answers about the evidence around single–dose HPV vaccination, and the current policy landscape.

As of March 2026, more than 90 countries have adopted a single-dose HPV vaccination schedule. This brief summarizes critical study findings, estimated public health impacts, and current recommendations to assist policymakers with decision-making.

Sub-Saharan Africa has made remarkable progress, yet approximately 490 mothers and more than 7,500 children under five years still die every day.As global health funding decreases, protecting decades of progress and continuing to build toward a healthier future will require tackling persistent bottlenecks, strengthening civil society advocacy, and coordinating leadership across sectors. What is needed now is bold, sustained political will to ensure every mother, newborn, and child survives and thrives.This published MNCH advocacy resource includes a Sub-Saharan Africa overview brief and country-specific briefs for Zambia, Uganda, Ethiopia, and Tanzania. Together, they outline key calls to action policymakers, funders, and advocates to accelerate the progress needed to improve health outcomes for mothers and children.