PATH hosted the 2022 Vaccines Against Shigella and ETEC (VASE) Conference on November 29 to December 1, 2022, in Washington, DC. This international event shared cutting-edge research related to the development of vaccines against neglected diarrheal pathogens including Shigella, enterotoxigenic Escherichia coli (ETEC), Campylobacter, and non-typhoidal Salmonella. PATH received 139 abstracts for consideration in the scientific content of the meeting, and the final conference program featured 24 abstract-based oral presentations and 87 abstract-based poster presentations. This booklet provides the complete abstracts for all oral and poster presentations at VASE 2022.