This issue of Directions in Global Health features work by OneWorld Health, PATH’s drug development program, to lead development of innovative methods to enhance the supply of artemisinin, a key ingredient in malaria treatments. It includes a commentary by Dr. Ponni Subbiah, who directs PATH’s drug development efforts. Other articles cover work to improve cervical cancer screening, protect infants from respiratory syncytial virus, increase access to family planning, and strengthen and expand use of human milk banking.