Critical gains in maternal, newborn, and child health across the globe during the past two decades provide inspiration for achieving the new vision set out through the recently ratified Sustainable Development Goals. These goals, combined with the launch of the Global Strategy for Women’s, Children’s, and Adolescents’ Health, embolden PATH to do even more to accelerate innovation to achieve the world we aspire to live in—a world where all women, newborns, children, and adolescents enjoy healthy and productive lives.