PET-PCR Method for Supporting Malaria Elimination Infection Identification as Part of a Field Trial in Mass Drug Administration in Southern Zambia

This study aimed to identify infections below the level of detection of the HRP2-based RDTs used to screen a cohort of individuals followed longitudinally in a randomized control trial. A negative RDT was highly predictive of a true negative, however a positive RDT was only correct half the time. RDT-positive/PCR-negative samples were likely to have been recently treated and cleared of parasites.

Publication date: November 2016

PET-PCR method for supporting malaria elimination infection identification as part of a field trial in mass drug administration in southern Zambia

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