This report presents the results of demonstration projects and other activities undertaken in Vietnam as part of a partnership between project Optimize (a collaboration between the World Health Organization and PATH) and Vietnam’s Ministry of Health. The activities aimed to demonstrate innovations in the supply chain that can help meet the demands of an increasingly large and costly portfolio of vaccines. For a summary of Optimize’s activities conducted with Vietnam’s National Expanded Program on Immunization, see Summary of Optimize Activities Conducted With Vietnam's National Expanded Programme on Immunization.