In 2010, the World Health Organization (WHO) issued a new policy to guide activities for controlling tuberculosis (TB) infection. This report provides guidance on advocacy for political and financial support for TB infection control from donors and countries, widespread adoption of the WHO policy, and incorporation of it into national and local policies. The report also addresses advocacy for linkages with civil society organizations in the field to ensure demand for and implementation of the WHO policy to protect health workers, patients, and communities from TB transmission.