Measuring Impact of Streptococcus pneumoniae and Haemophilus influenzae type b Conjugate Vaccination

This manual describes approaches to measuring pneumococcal and Haemophilus influenzae type b conjugate vaccine impact on disease incidence and provides a framework for determining the best methodology in a specific country setting. It details a variety of study designs and includes sample protocols and data-collection instruments for a case-control study to assess conjugate vaccine effectiveness against invasive pneumococcal disease.

Author(s): World Health Organization

Published: 2012