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Refinement of a Human Challenge Model for Evaluation of Enterotoxigenic Escherichia coli Vaccines

This article, published in Clinical and Vaccine Immunology, reports on a study which found that a lower dose than used previously of the human challenge model for enterotoxigenic Escherichia coli diarrhea using strain H10407 is sufficient for determining the effectiveness of a vaccine candidate.

Author: Harro C, Chakraborty S, Feller A, et al.

Published: 2011

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(Located at cvi.asm.org)

Citation: Harro C, Chakraborty S, Feller A, et al. Refinement of a Human Challenge Model for Evaluation of Enterotoxigenic Escherichia coli Vaccines. Clinical and Vaccine Immunology. 2011;18(10):1719-1727. 

Resource types: Peer-reviewed journal

Diseases/vaccines: Shigellosis and enterotoxigenic Escherichia coli (ETEC)

Topics: Disease/vaccine specific information

Regions: Global