Browse resources

Disease: Meningococcus

Total results with these characteristics: 193

Immunogenicity and Safety of a New Meningococcal A Conjugate Vaccine in Indian Children Aged 2-10 Years: A Phase II/III Double-Blind Randomized Controlled Trial

This article, published in Vaccine, describes a study that compared the immunogenicity and safety of a single dose of a new meningococcal A conjugate vaccine (PsA-TT, MenAfriVac™, Serum Institute of India Ltd.) against the meningococcal group …

Author: Hirve S, Bavdekar A, Pandit A, et al.

Published: 2012

The Immunological Basis for Immunization Series

This web page provides links to individual disease/vaccine-specific modules that are intended to give immunization managers and vaccination professionals a brief and easy-to-understand overview of the scientific basis of vaccination, as well as the …

Author: World Health Organization

Impact of Meningococcal Serogroup C Conjugate Vaccines on Carriage and Herd Immunity

This article, published in the Journal of Infectious Diseases, investigates the impact of meningococcal serogroup C conjugate vaccine introduction in the United Kingdom on asymptomatic carriage of meningococci to establish whether …

Author: Maiden MCJ, Ibarz-Pavón AB, Urwin R, et al.

Published: 2008

The Impact of Protein-Conjugate Polysaccharide Vaccines: An Endgame for Meningitis?

The impact of conjugate polysaccharide vaccines on disease is largely due to their effectiveness against asymptomatic carriage of bacteria. This reduces transmission, resulting in herd immunity; however, the effect on carriage can result in the …

Author: Maiden MCJ

Published: 2013

Impact of the Serogroup A Meningococcal Conjugate Vaccine, MenAfriVac, on Carriage and Herd Immunity

The conjugate vaccine against serogroup A Neisseria meningitidis (NmA), MenAfriVac, was first introduced in mass vaccination campaigns of 1 to 29-year-olds in Burkina Faso in 2010. The authors of this article, published in Clinical Infectious …

Author: Kristiansen PA, Diomandé F, Ba AK, et al.

Published: 2013

Implementation of Standard Operating Procedures for Enhanced Meningitis Surveillance in 13 Countries of the African Meningitis Belt from 2003 to 2008

This poster, presented at the 2008 International Pathogenic Neisseria Conference, displays the results of a study to determine the effectiveness of the Standard Operating Procedures that were developed in 2001 to 2002 to codify and enhance …

Author: Djingarey MH, Konde K, Kandolo D, et al.

Published: 2008

The Implications of Vaccines for Prevention of Bacterial Meningitis

Although existing conjugate vaccines protect against some types of bacterial meningitis, new vaccines are needed to broaden protection against the disease. Published in Current Opinion in Neurology, this article posits new uses for existing vaccines …

Author: Riordan A

Published: 2010

Increased Incidence of Meningococcal Disease in HIV-Infected Individuals Associated With Higher Case-Fatality Ratios in South Africa

This article, published in AIDS, describes a cohort surveillance study conducted in South Africa to compare the incidence of meningococcal disease among HIV-infected individuals versus uninfected individuals. The authors also evaluated the extent to …

Author: Cohen C, Singh E, Wu HM, et al.

Published: 2010

Increasing Access to Lifesaving Vaccines: PATH Closes the Immunization Gap Through Innovation and Collaboration

This fact sheet outlines PATH's work on vaccines and immunization. Topic areas include developing affordable vaccines, designing innovative vaccine technologies, and expanding uptake of existing vaccines. These efforts reduce the burden of malaria, …

Author: PATH

Published: 2013

Indian Academy of Pediatrics Committee on Immunisation

This website from the Indian Academy of Pediatrics provides up-to-date information on vaccination for the general public and heath care professionals. It provides a range of resources including information about the latest recommendations by …

Author: Indian Academy of Pediatrics Committee on Immunisation

Infectious Disease: An Ill Wind, Bringing Meningitis

This commentary, published in the journal Science, discusses meningococcal meningitis epidemics in Africa that come with the onset of the dry season, and the vaccines in development that could limit the disease's impact. ABSTRACT ONLY. (Learn …

Author: Roberts L

Published: 2008

Infectious Disease: Hitting Early, Epidemic Meningitis Ravages Nigeria and Niger

This commentary, published in the journal Science, discusses one of the worst meningococcal meningitis epidemics in years in Nigeria and Niger. ABSTRACT ONLY. (Learn how users in developing countries can gain free access to journal …

Author: Roberts L

Published: 2009

Innovating to Improve Health: PATH Develops and Delivers Novel Solutions for Those Who Need Them Most

This fact sheet provides an overview of PATH's work to develop and deliver innovative health solutions for those who need them most. These solutions range from developing and introducing affordable, appropriate technologies to creating conditions …

Author: PATH

Published: 2012

Intercountry Meningitis Meeting: Preparing for the Next Epidemic Seasons, Mali, October 2006

This article, published in the World Health Organization's Weekly Epidemiological Record, summarizes an intercountry meeting on enhanced surveillance and responses to meningitis epidemics held in October 2006 in Bamako, Mali. More than 80 …

Author: World Health Organization

Published: 2007

Introducing New Vaccines Into Developing Countries: Obstacles, Opportunities, and Complexities

This commentary, published in Nature Medicine, reviews current trends that may affect whether the most promising of the 350 vaccine candidates under development will eventually be used in programs for the poor in developing countries. It also …

Author: Clemens J, Jodar L

Published: 2005

Invasive Meningococcal Disease Epidemiology and Control Measures: A Framework for Evaluation

This article, published in BMC Public Health, describes a discrete event simulation of the epidemiology of invasive meningococcal disease to quantify the potential impact of implementing routine vaccination of adolescents in the United States with a …

Author: Caro JJ, Möller J, Getsios D, et al.

Published: 2007

Investigation of Different Group A Immunoassays Following One Dose of Meningococcal Group A Conjugate Vaccine or A/C Polysaccharide Vaccine in Adults

This article, published in Clinical and Vaccine Immunology, details further analysis of the sera from a previous Phase 1 study to assess the safety, immunogenicity, and antibody persistence of a new group A conjugate vaccine, using four additional …

Author: Findlow H, Plikaytis BD, Aase A, et al.

Published: 2009

Is it Exposure to Cigarette Smoke or to Smokers Which Increases the Risk of Meningococcal Disease in Teenagers?

This article, published in the International Journal of Epidemiology, reports on a study that aimed to determine whether passive smoking, which appears to increase the risk of meningococcal disease in adolescents, is attributable to …

Author: Coen PG, Tully J, Stuart JM, et al.

Published: 2006

Kill or Cure: Meningitis

This 25-minute BBC World documentary, produced by Rockhopper TV, offers a poignant and revealing account of the devastating impact meningitis epidemics have on individuals, families, and communities. The film also takes viewers to Mali where PATH's …

Author: PATH; Rockhopper TV

Published: 2007

Laboratory Quality Control in a Multicentre Meningococcal Carriage Study in Burkina Faso

To investigate the potential herd immunity effect of MenAfriVac™, a new conjugate vaccine against serogroup A Neisseria meningitidis, the authors of this article, published in Transactions of the Royal Society of Tropical …

Author: Kristiansen PA, Ouédraogo AS, Sanou I, et al.

Published: 2012

Landscape Analysis: Trends in Vaccine Availability and Novel Vaccine Delivery Technologies: 2008–2025

This landscape analysis identifies trends in the availability of vaccines and novel vaccine delivery technologies that are and will be of relevance to low- and middle-income countries from the present through 2025.

Author: PATH, World Health Organization

Published: 2008

Lessons From Meningococcal Carriage Studies

This article, published in FEMS Microbiology Reviews, reviews previous meningococcal carriage studies in European countries in order to learn more about the disease and the potential impact of mass vaccination with meningococcal vaccines. The …

Author: Caugant DA, Tzanakaki G, Kriz P

Published: 2007

Making New Vaccines Affordable: A Comparison of Financing Processes Used to Develop and Deploy New Meningococcal and Pneumococcal Conjugate Vaccines

Two innovative mechanisms have been used to accelerate the development of low-price supply lines for conjugate vaccines. The Meningitis Vaccine Project is a so-called push mechanism that facilitated technology transfer to an Indian company to …

Author: Hargreaves JR, Greenwood B, Clift C, et al.

Published: 2011

Manson Lecture. Meningococcal Meningitis in Africa

This article, published in Transactions of the Royal Society of Tropical Medicine and Hygiene, covers the history of meningococcal meningitis in Africa since epidemics of the infection were first described around 100 years ago. The article also …

Author: Greenwood B

Published: 1999

MenAfriCar - African Meningococcal Carriage Consortium

MenAfriCar is a global research effort to study how meningococcal meningitis is spread in Africa and to document the impact of a new meningitis vaccine on reducing transmission. This website provides an overview of the consortium's aims, objectives, …

Author: MenAfriCar